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Article

RAS mutations in thyroid FNA specimens are highly predictive of predominantly low-risk follicular-pattern cancers.

The Journal of clinical endocrinology and metabolism - 1 May 2013

Gupta Nikhil, Dasyam Anil K, Carty Sally E, Nikiforova Marina N, Ohori N Paul, Armstrong Michaele, Yip Linwah, LeBeau Shane O, McCoy Kelly L, Coyne Christopher, Stang Michael T, Johnson Jonas, Ferris Robert L, Seethala R, Nikiforov Yuri E, Hodak Steven P

Abstract excerpt

INTRODUCTION: RAS mutations are common in thyroid tumors and confer a high risk of cancer when detected in fine-needle aspiration (FNA) specimens. Specific characteristics of RAS-positive thyroid cancers are not well described. METHODS: From April 2007 to April 2009, 921 consecutive patients undergoing FNA were evaluated prospectively with a panel of molecular markers. Ultrasonographic, cytological, histological,...

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Share to Adenocarcinoma, Follicular
Share to Biopsy, Fine-Needle

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Predictive Value of Tests

Share to Thyroid Gland

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Identifiers

PMID: 23539734
DOI: 10.1210/jc.2012-3396
PMCID: PMC5393462

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