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Article

Preoperative detection of RAS mutation may guide extent of thyroidectomy.

Surgery - 1 Jan 2017

Patel Snehal G, Carty Sally E, McCoy Kelly L, Ohori N Paul, LeBeau Shane O, Seethala Raja R, Nikiforova Marina N, Nikiforov Yuri E, Yip Linwah

Abstract excerpt

BACKGROUND: Preoperative detection of RAS mutations can contribute to cancer risk assessment in indeterminate thyroid nodules, although RAS is not always associated with malignancy. METHODS: Fine-needle aspiration samples classified in 1 of 3 indeterminate cytology categories were prospectively tested for N-, H-, and K-RAS mutations using next-generation sequencing assay. RESULTS: In the study, 93 patients with...

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Share to Biopsy, Fine-Needle
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Proto-Oncogene Proteins p21(ras)

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Share to Thyroid Neoplasms

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Source

Open in PubMed Open full text

Identifiers

PMID: 27863786
DOI: 10.1016/j.surg.2016.04.054
PMCID: PMC5497309

Genes

HRAS
NRAS
KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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