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Clinical utility of RAS mutations in thyroid cancer: a blurred picture now emerging clearer

27 Jan 2016

Abstract excerpt

RAS mutations play an important role in thyroid tumorigenesis. Considerable effort has been made in the last decade to apply RAS mutations as molecular markers to the clinical management of thyroid nodules and thyroid cancer. Yet, for the low diagnostic sensitivities and specificities of RAS mutations, when used alone, and for their uncertain role in the clinical outcomes of thyroid cancer, it has been unclear...

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PMID: 26817707
DOI: 10.1186/s12916-016-0559-9

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