Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Obesity-related genetic variants, human pigmentation, and risk of melanoma.

Human genetics - 1 Jul 2013

Li Xin, Liang Liming, Zhang Mingfeng, Song Fengju, Nan Hongmei, Wang Li-E, Wei Qingyi, Lee Jeffrey E, Amos Christopher I, Qureshi Abrar A, Han Jiali

Abstract excerpt

Previous biological studies showed evidence of a genetic link between obesity and pigmentation in both animal models and humans. Our study investigated the individual and joint associations between obesity-related single nucleotide polymorphisms (SNPs) and both human pigmentation and risk of melanoma. Eight obesity-related SNPs in the FTO, MAP2K5, NEGR1, FLJ35779, ETV5, CADM2, and NUDT3 genes were nominally...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Case-Control Studies
Share to Linkage Disequilibrium

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Melanoma

Share to Obesity

Share to Pigmentation

Share to Polymorphism, Single Nucleotide

Share to Risk Factors

Share to White People

Source

Open in PubMed Open full text

Identifiers

PMID: 23539184
DOI: 10.1007/s00439-013-1293-4
PMCID: PMC3683389

Genes

FTO
CADM2
ETV5
NEGR1
NUDT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Obesity-related genetic variants, human pigmentation, and risk of melanoma.PMID 23539184Read ↗

A variant in FTO shows association with melanoma risk not due to BMI.Semantic proximity Read ↗

Genetics of pigmentation and melanoma predisposition.Semantic proximity Read ↗

Sex-specific genetic effects associated with pigmentation, sensitivity to sunlight, and melanoma in a population of Spanish originSemantic proximity Read ↗

Genetic markers of pigmentation are novel risk loci for uveal melanoma.Semantic proximity Read ↗

Skin pigmentation polymorphisms associated with increased risk of melanoma in a case-control sample from southern Brazil.Semantic proximity Read ↗

Genome-wide association studies identify several new loci associated with pigmentation traits and skin cancer risk in European Americans.Semantic proximity Read ↗

Multiple pigmentation gene polymorphisms account for a substantial proportion of risk of cutaneous malignant melanoma.Semantic proximity Read ↗

Pigmentation-related genes and their implication in malignant melanoma susceptibility.Semantic proximity Read ↗

Genome-wide association meta-analysis of individuals of European ancestry identifies new loci explaining a substantial fraction of hair color variation and heritability.Semantic proximity Read ↗

The Genetics of Human Skin and Hair PigmentationSemantic proximity Read ↗

Comprehensive candidate gene study highlights UGT1A and BNC2 as new genes determining continuous skin color variation in Europeans.Semantic proximity Read ↗

Current opportunities and challenges: genome-wide association studies on pigmentation and skin cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.