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Article

Comprehensive candidate gene study highlights UGT1A and BNC2 as new genes determining continuous skin color variation in Europeans.

Human genetics - 1 Feb 2013

Jacobs Leonie C, Wollstein Andreas, Lao Oscar, Hofman Albert, Klaver Caroline C, Uitterlinden André G, Nijsten Tamar, Kayser Manfred, Liu Fan

Abstract excerpt

Natural variation in human skin pigmentation is primarily due to genetic causes rooted in recent evolutionary history. Genetic variants associated with human skin pigmentation confer risk of skin cancer and may provide useful information in forensic investigations. Almost all previous gene-mapping studies of human skin pigmentation were based on categorical skin color information known to oversimplify the...

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Source

Identifiers

PMID: 23052946
DOI: 10.1007/s00439-012-1232-9

Genes

BNC2
ASIP
HERC2
OCA2
TYR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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