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Article

DOC2B and Munc13-1 differentially regulate neuronal network activity.

Cerebral cortex (New York, N.Y. : 1991) - 1 Sept 2014

Lavi Ayal, Sheinin Anton, Shapira Ronit, Zelmanoff Daniel, Ashery Uri

Abstract excerpt

Alterations in the levels of synaptic proteins affect synaptic transmission and synaptic plasticity. However, the precise effects on neuronal network activity are still enigmatic. Here, we utilized microelectrode array (MEA) to elucidate how manipulation of the presynaptic release process affects the activity of neuronal networks. By combining pharmacological tools and genetic manipulation of synaptic proteins,...

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Identifiers

PMID: 23537531
DOI: 10.1093/cercor/bht081
PMCID: PMC4128701

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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