Article
Genetic diversity and signatures of selection of drug resistance in Plasmodium populations from both human and mosquito hosts in continental Equatorial Guinea.
Malaria journal - 27 Mar 2013
Mendes Cristina, Salgueiro Patrícia, Gonzalez Vicenta, Berzosa Pedro, Benito Agustin, do Rosário Virgílio E, de Sousa Bruno, Cano Jorge, Arez Ana Paula
Abstract excerpt
BACKGROUND: In Plasmodium, the high level of genetic diversity and the interactions established by co-infecting parasite populations within the same host may be a source of selection on pathogen virulence and drug resistance. As different patterns have already been described in humans and mosquitoes, parasite diversity and population structure should be studied in both hosts to properly assess their effects on...
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