Article
Diet folate, DNA methylation and polymorphisms in methylenetetrahydrofolate reductase in association with the susceptibility to gastric cancer.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2013
Gao Shang, Ding Li-Hong, Wang Jian-Wei, Li Cun-Bao, Wang Zhao-Yang
Abstract excerpt
Methylenetetrahydrofolate reductase (MTHFR) has been reported to be associated with DNA methylation, an epigenetic feature frequently found in gastric cancer. We conducted a case-control study to explore the association of MTHFR C677T polymorphisms with gastric cancer risk and its relation with the DNA methylation of COX-2, MGMT, and hMLH1 genes. Genotyping of P16, MGMT and HMLH1 was determined by...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
