Article
Impact of methylenetetrahydrofolate reductase polymorphisms and folate intake on the risk of gastric cancer and their association with Helicobacter pylori infection and tumor site.
Genetics and molecular research : GMR - 24 Jan 2014
Chen J, Yuan L, Duan Y Q, Jiang J Q, Zhang R, Huang Z J, Xiao X R
Abstract excerpt
Folic acid and methylenetetrahydrofolate reductase (MTHFR) may both affect the development of human cancer. We conducted a population-based case-control study in a Chinese population to investigate the potential role of folate intake and MTHFR gene polymorphisms in gastric cancer, and their interaction with infection by Helicobacter pylori and tumor location. A total of 767 patients with newly diagnosed gastric...
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