Article
Common variations of DNA repair genes are associated with response to platinum-based chemotherapy in NSCLCs.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2013
Li Xian-Dong, Han Ji-Chang, Zhang Yi-Jie, Li Hong-Bing, Wu Xue-Yan
Abstract excerpt
AIM: Individual differences in chemosensitivity and clinical outcome of non-small-cell lung cancer (NSCLC) patients may be induced by host inherited factors. We investigated the impact of XPD Arg156Arg, XPD Asp312Asn, XPD Asp711Asp and XPD Lys751Gln gene polymorphisms on the efficacy of platinum-based chemotherapy in NSCLC patients. METHODS: A total of 496 were consecutively selected from the Affiliated Hospital...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
