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Article

Association of UGT1A1*28 polymorphisms with irinotecan-induced toxicities in colorectal cancer: a meta-analysis in Caucasians.

The pharmacogenomics journal - 1 Apr 2014

Liu X, Cheng D, Kuang Q, Liu G, Xu W

Abstract excerpt

A meta-analysis in Caucasians was conducted to investigate the possible association of uridine diphosphate glucuronosyltransferase (UGT) 1A1 gene polymorphisms with irinotecan (IRI)-induced neutropenia and diarrhoea in colorectal cancer (CRC). We searched PubMed and Embase until May 2012 to identify eligible studies, extracted data, assessed methodological quality, and performed statistical analysis using REVMAN...

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Identifiers

PMID: 23529007
DOI: 10.1038/tpj.2013.10
PMCID: PMC3992871

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