Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Finding the missing heritability in pediatric obesity: the contribution of genome-wide complex trait analysis.

International journal of obesity (2005) - 1 Nov 2013

Llewellyn C H, Trzaskowski M, Plomin R, Wardle J

Abstract excerpt

Known single-nucleotide polymorphisms (SNPs) explain <2% of the variation in body mass index (BMI) despite the evidence of >50% heritability from twin and family studies, a phenomenon termed 'missing heritability'. Using DNA alone for unrelated individuals, a novel method (in a software package c...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Body Mass Index
Share to Genome-Wide Association Study
Share to Models, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Pediatric Obesity

Share to Quantitative Trait, Heritable

Share to Software

Share to United Kingdom

Source

Open in PubMed Open full text

Identifiers

PMID: 23528754
DOI: 10.1038/ijo.2013.30
PMCID: PMC3826033

Genes

SDS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23528754-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Finding the missing heritability in pediatric obesity: the contribution of genome-wide complex trait analysis.PMID 23528754Read ↗

From modeling to measurement: developmental trends in genetic influence on adiposity in childhood.Semantic proximity Read ↗

Trans-ancestry genome-wide association study of childhood body mass index identifies novel loci and age-specific effects.Semantic proximity Read ↗

Evidence for a strong genetic influence on childhood adiposity despite the force of the obesogenic environment.Semantic proximity Read ↗

Genetic and environmental effects on body mass index from infancy to the onset of adulthood: an individual-based pooled analysis of 45 twin cohorts participating in the COllaborative project of Development of Anthropometrical measures in Twins (CODATwins) study.Semantic proximity Read ↗

The CODATwins Project: The Cohort Description of Collaborative Project of Development of Anthropometrical Measures in Twins to Study Macro-Environmental Variation in Genetic and Environmental Effects on Anthropometric Traits.Semantic proximity Read ↗

Missing heritability: is the gap closing? An analysis of 32 complex traits in the Lifelines Cohort Study.Semantic proximity Read ↗

Twins and the mystery of missing heritability: the contribution of gene-environment interactions.Semantic proximity Read ↗

Parental and child genetic contributions to obesity traits in early life based on 83 loci validated in adults: the FAMILY study.Semantic proximity Read ↗

Novel loci for childhood body mass index and shared heritability with adult cardiometabolic traits.Semantic proximity Read ↗

Genome-wide analysis reveals extensive genetic overlap between childhood phenotypes and later-life type 2 diabetes.Semantic proximity Read ↗

Assessing the contribution of rare variants to complex trait heritability from whole-genome sequence data.Semantic proximity Read ↗

Estimating genetic nurture with summary statistics of multi-generational genome-wide association studiesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.