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Article

Association between granzyme B and perforin I polymorphisms and allograft outcomes in Hispanic kidney transplant recipients.

Clinical transplantation - 1 Jan 2000

Corrales-Tellez Eglis, Vu Don, Shah Tariq, Hutchinson Ian, Min David I

Abstract excerpt

Granzyme B (GZMB) and perforin 1 gene (PRF1) are key effector molecules of cytotoxic T lymphocytes, in causing acute and chronic solid organ transplant rejection. In this study, we analyzed the impact of GZMB and PRF1 polymorphism on kidney allograft outcomes. In all, 527 de novo kidney Hispanic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23528102
DOI: 10.1111/ctr.12114

Genes

PRF1
GZMB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23528102-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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