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Article

Loss of MicroRNA-155 Protects the Heart From Pathological Cardiac Hypertrophy

22 Mar 2014

Abstract excerpt

RATIONALE: In response to mechanical and pathological stress, adult mammalian hearts often undergo mal-remodeling, a process commonly characterized as pathological hypertrophy, which is associated with upregulation of fetal genes, increased fibrosis, and reduction of cardiac dysfunction. The molecular pathways that regulate this process are not fully understood. OBJECTIVE: To explore the function of microRNA-155...

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Share to Cardiac Fibrosis and Remodeling
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Identifiers

PMID: 24657879
DOI: 10.1161/circresaha.114.303784

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