Article
Cytotoxic mechanism of Piper gaudichaudianum Kunth essential oil and its major compound nerolidol.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association - 1 Jul 2013
Sperotto A R M, Moura D J, Péres V F, Damasceno F C, Caramão E B, Henriques J A P, Saffi J
Abstract excerpt
Piper gaudichaudianum Kunth is used in popular medicine as anti-inflamatory and against liver disorders. One of the most studied components of the plant is the essential oil for which chemical analysis revealed (E)-nerolidol as major compound. Recently, we have shown that P. gaudichaudianum essential oil possesses strong cytotoxic effects in mammalian V79 cells. The aim of this study was to analyze the...
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