Article
Complex modulation of the Aedes aegypti transcriptome in response to dengue virus infection.
PloS one - 1 Jan 2012
Bonizzoni Mariangela, Dunn W Augustine, Campbell Corey L, Olson Ken E, Marinotti Osvaldo, James Anthony A
Abstract excerpt
Dengue fever is the most important arboviral disease world-wide, with Aedes aegypti being the major vector. Interactions between the mosquito host and dengue viruses (DENV) are complex and vector competence varies among geographically-distinct Ae. aegypti populations. Additionally, dengue is caused by four antigenically-distinct viral serotypes (DENV1-4), each with multiple genotypes. Each virus genotype...
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