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Article

DNA repair alterations in common pediatric malignancies.

Medical science monitor : international medical journal of experimental and clinical research - 1 Jan 2008

Papaefthymiou Maria A, Giaginis Costas T, Theocharis Stamatios E

Abstract excerpt

DNA repair is an important defense mechanism against DNA damage and includes four distinct pathways: direct, excision, mismatch, and double-strand break repair systems. Recent evidence suggests that alterations in proteins participating in the DNA repair systems may result in cellular senescence, cell death, and neoplastic transformation. Malignancies in adulthood exhibit genomic instability and an increased...

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Identifiers

PMID: 18160950

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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