Article
Diagnostic and prognostic value of immunocytochemistry and BRAF mutation analysis on liquid-based biopsies of thyroid neoplasms suspicious for carcinoma.
European journal of endocrinology - 1 Jun 2013
Rossi Esther Diana, Martini Maurizio, Capodimonti Sara, Straccia Patrizia, Cenci Tonia, Lombardi Celestino Pio, Pontecorvi Alfredo, Larocca Luigi Maria, Fadda Guido
Abstract excerpt
OBJECTIVE: In the field of fine-needle aspiration cytology, the category of suspicious for malignancy (SM) thyroid lesions, that bears 55-85% risk of malignant histology, is a challenging topic in which morphology alone is not always able to make a correct diagnosis. Recently, immunocytochemistry (ICC) has been referred to as helpful in differentiating low- and high-malignant risk lesions and BRAF activating...
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