Article
Needles in the genetic haystack of lipid disorders: single nucleotide polymorphisms in the microRNA regulome.
Journal of lipid research - 1 May 2013
Sethupathy Praveen
Abstract excerpt
In recent years, microRNAs (miRNA) have emerged as important posttranscriptional regulators of gene expression in a wide variety of biological pathways. Since the discovery of the liver-specific miRNA-122 (miR-122) and its critical role in hepatic function, numerous additional miRNAs have been implicated in lipid metabolism. It is now apparent that lipid homeostasis is governed in part by an intricate web of...
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