Article
Genetic regulation of human adipose microRNA expression and its consequences for metabolic traits.
Human molecular genetics - 1 Aug 2013
Civelek Mete, Hagopian Raffi, Pan Calvin, Che Nam, Yang Wen-pin, Kayne Paul S, Saleem Niyas K, Cederberg Henna, Kuusisto Johanna, Gargalovic Peter S, Kirchgessner Todd G, Laakso Markku, Lusis Aldons J
Abstract excerpt
The genetics of messenger RNA (mRNA) expression has been extensively studied in humans and other organisms, but little is known about genetic factors contributing to microRNA (miRNA) expression. We examined natural variation of miRNA expression in adipose tissue in a population of 200 men who have been carefully characterized for metabolic syndrome (MetSyn) phenotypes as part of the Metabolic Syndrome in Men...
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