Article
The human flavoproteome.
Archives of biochemistry and biophysics - 15 Jul 2013
Lienhart Wolf-Dieter, Gudipati Venugopal, Macheroux Peter
Abstract excerpt
Vitamin B2 (riboflavin) is an essential dietary compound used for the enzymatic biosynthesis of FMN and FAD. The human genome contains 90 genes encoding for flavin-dependent proteins, six for riboflavin uptake and transformation into the active coenzymes FMN and FAD as well as two for the reduction to the dihydroflavin form. Flavoproteins utilize either FMN (16%) or FAD (84%) while five human flavoenzymes have a...
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