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Article

Electron transfer flavoprotein and its role in mitochondrial energy metabolism in health and disease.

Gene - 15 Apr 2021

Henriques Bárbara J, Katrine Jentoft Olsen Rikke, Gomes Cláudio M, Bross Peter

Abstract excerpt

Electron transfer flavoprotein (ETF) is an enzyme with orthologs from bacteria to humans. Human ETF is nuclear encoded by two separate genes, ETFA and ETFB, respectively. After translation, the two subunits are imported to the mitochondrial matrix space and assemble into a heterodimer containing one FAD and one AMP as cofactors. ETF functions as a hub taking up electrons from at least 14 flavoenzymes, feeding...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33450351
DOI: 10.1016/j.gene.2021.145407
PMCID: PMC7949704

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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