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Article

Disorders of flavin adenine dinucleotide metabolism: MADD and related deficiencies.

The international journal of biochemistry & cell biology - 1 Mar 2021

Mereis Michelle, Wanders Ronald J A, Schoonen Maryke, Dercksen Marli, Smuts Izelle, van der Westhuizen Francois H

Abstract excerpt

Multiple acyl-coenzyme A dehydrogenase deficiency (MADD), or glutaric aciduria type II (GAII), is a group of clinically heterogeneous disorders caused by mutations in electron transfer flavoprotein (ETF) and ETF-ubiquinone oxidoreductase (ETFQO) - the two enzymes responsible for the re-oxidation of enzyme-bound flavin adenine dinucleotide (FADH2) via electron transfer to the respiratory chain at the level of...

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Identifiers

PMID: 33279678
DOI: 10.1016/j.biocel.2020.105899

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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