Article
History, Pathogenesis, and Management of Familial Gastric Cancer: Original Study of John XXIII's Family
26 Dec 2012
Abstract excerpt
BACKGROUND: Hereditary diffuse gastric cancer is associated with the E-cadherin germline mutations, but genetic determinants have not been identified for familial intestinal gastric carcinoma. The guidelines for hereditary diffuse gastric cancer are clearly established; however, there are no defined recommendations for the management of familial intestinal gastric carcinoma. METHODS: In this study we describe...