Article
The identification of pathway markers in intracranial aneurysm using genome-wide association data from two different populations.
PloS one - 1 Jan 2013
Bakir-Gungor Burcu, Sezerman Osman Ugur
Abstract excerpt
The identification of significant individual factors causing complex diseases is challenging in genome-wide association studies (GWAS) since each factor has only a modest effect on the disease development mechanism. In this study, we hypothesize that the biological pathways that are targeted by these individual factors show higher conservation within and across populations. To test this hypothesis, we searched...
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