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Article

Genetic predisposition to left ventricular hypertrophy and the potential involvement of cystatin-C in untreated hypertension.

American journal of hypertension - 1 May 2013

Tousoulis Dimitris, Androulakis Emmanuel, Papageorgiou Nikolaos, Miliou Antigoni, Chatzistamatiou Evaggelos, Oikonomou Evaggelos, Moustakas George, Kallikazaros Ioannis, Stefanadis Christodoulos

Abstract excerpt

BACKGROUND: The angiotensinogen M235T and aldosterone synthase C-344T gene polymorphisms have been associated with cardiac and structure function. However, these associations in untreated hypertension remain unknown. We examined whether these variants determined both echocardiography indices and the potential associated underlying mechanisms, including cystatin-C and vascular inflammation. METHODS: The study...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Cytochrome P-450 CYP11B2

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Share to Hypertrophy, Left Ventricular

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Source

Identifiers

PMID: 23479071
DOI: 10.1093/ajh/hps089

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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