Article
Genome-wide association studies of hematologic phenotypes: a window into human hematopoiesis.
Current opinion in genetics & development - 1 Jun 2013
Sankaran Vijay G, Orkin Stuart H
Abstract excerpt
The study of human hematopoiesis is often limited by the inability to manipulate this process in vivo and differences that exist between humans and commonly employed model organisms. However, human genetics provides a way to gain insight into natural variation in a variety of hematologic phenotypes and creates an opportunity to better understand hematopoiesis. In this review, we discuss how genome-wide...
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