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Rat mutations cvd and hob with cerebellar malformations map to chromosome 2.

Experimental animals - 1 Jan 2004

Kuwamura Mitsuru, Ando Yosuke, Takada Akiko, Kanehara Toshiko, Yamate Jyoji, Kotani Takao, Takeshita Shigehito, Kanbori Miyuki, Kitada Kazuhiro, Serikawa Tadao

Abstract excerpt

In this paper, we executed genome mapping and comparative mapping analyses for cvd and hob, autosomal recessive mutations with cerebellar vermis defect and cerebellar dysplasia in the rat. For the linkage analysis, we produced three sets of backcross progeny, (ACI x CVD)F(1) and (F344 x CVD)F(1) females crossed to a cvd homozygous male rat, and (HOB x WKY)F(1) males crossed to hob homozygous female rats. Analysis...

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PMID: 14993736
DOI: 10.1538/expanim.53.21

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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