Article
Prevalence and patterns of morphological abnormalities in patients with childhood cancer.
JAMA - 2 Jan 2008
Merks Johannes H M, Ozgen Heval M, Koster Jan, Zwinderman Aeilko H, Caron Huib N, Hennekam Raoul C M
Abstract excerpt
CONTEXT: Constitutional gene defects predispose to cancer in children. Such tumor predisposition syndromes can be recognized by specific patterns of morphological abnormalities. OBJECTIVES: To assess the prevalence of morphological abnormalities in a large cohort of patients with childhood cancer and to identify new tumor predisposition syndromes. DESIGN, SETTING, AND PARTICIPANTS: Patients were recruited from...
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