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Article

Orientations and proximities of the extracellular ends of transmembrane helices S0 and S4 in open and closed BK potassium channels.

PloS one - 1 Jan 2013

Niu Xiaowei, Liu Guoxia, Wu Roland S, Chudasama Neelesh, Zakharov Sergey I, Karlin Arthur, Marx Steven O

Abstract excerpt

The large-conductance potassium channel (BK) α subunit contains a transmembrane (TM) helix S0 preceding the canonical TM helices S1 through S6. S0 lies between S4 and the TM2 helix of the regulatory β1 subunit. Pairs of Cys were substituted in the first helical turns in the membrane of BK α S0 an...

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Identifiers

PMID: 23472181
DOI: 10.1371/journal.pone.0058335
PMCID: PMC3589268

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Prepared record publication-23472181-2026-09-05.1. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 5 Sept 2026.

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