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Article

The AMPK family member Snf1 protects Saccharomyces cerevisiae cells upon glutathione oxidation.

PloS one - 1 Jan 2013

Pérez-Sampietro Maria, Casas Celia, Herrero Enrique

Abstract excerpt

The AMPK/Snf1 kinase has a central role in carbon metabolism homeostasis in Saccharomyces cerevisiae. In this study, we show that Snf1 activity, which requires phosphorylation of the Thr210 residue, is needed for protection against selenite toxicity. Such protection involves the Elm1 kinase, which acts upstream of Snf1 to activate it. Basal Snf1 activity is sufficient for the defense against selenite, although...

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Identifiers

PMID: 23472170
DOI: 10.1371/journal.pone.0058283
PMCID: PMC3589272

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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