Article
Developmental regulation of nucleolus size during Drosophila eye differentiation.
PloS one - 1 Jan 2013
Baker Nicholas E
Abstract excerpt
When cell cycle withdrawal accompanies terminal differentiation, biosynthesis and cellular growth are likely to change also. In this study, nucleolus size was monitored during cell fate specification in the Drosophila eye imaginal disc using fibrillarin antibody labeling. Nucleolus size is an indicator of ribosome biogenesis and can correlate with cellular growth rate. Nucleolar size was reduced significantly...
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