Article
Semiautomated isolation and molecular characterisation of single or highly purified tumour cells from CellSearch enriched blood samples using dielectrophoretic cell sorting.
British journal of cancer - 2 Apr 2013
Peeters D J E, De Laere B, Van den Eynden G G, Van Laere S J, Rothé F, Ignatiadis M, Sieuwerts A M, Lambrechts D, Rutten A, van Dam P A, Pauwels P, Peeters M, Vermeulen P B, Dirix L Y
Abstract excerpt
BACKGROUND: Molecular characterisation of single circulating tumour cells (CTCs) holds considerable promise for predictive biomarker assessment and to explore CTC heterogeneity. We evaluate a new method, the DEPArray system, that allows the dielectrophoretic manipulation and isolation of single and 100% purified groups of CTCs from pre-enriched blood samples and explore the feasibility of their molecular...
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