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Article

Identification of shared genes and pathways: a comparative study of multiple sclerosis susceptibility, severity and response to interferon beta treatment.

PloS one - 1 Jan 2013

Mahurkar Sunil, Moldovan Max, Suppiah Vijayaprakash, O'Doherty Catherine

Abstract excerpt

Recent genome-wide association studies (GWAS) have successfully identified several gene loci associated with multiple sclerosis (MS) susceptibility, severity or interferon-beta (IFN-ß) response. However, due to the nature of these studies, the functional relevance of these loci is not yet fully understood. We have utilized a systems biology based approach to explore the genetic interactomes of these MS related...

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Source

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Identifiers

PMID: 23469041
DOI: 10.1371/journal.pone.0057655
PMCID: PMC3585216

Genes

ABL1
FYN
GRB2
PLCG1
PRKCD
SRC
UBC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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