Article
A-kinase anchoring proteins 10 expression in relation to 2073A/G polymorphism and tumor progression in patients with colorectal cancer.
Pathology oncology research : POR - 1 Jul 2013
Wang Mojin, Zhang Dan, Wang Rui, Rui Yuanyi, Zhou Jin, Wang Rong, Zhou Bin, Huang Xiaoran, Yang Lie, Li Yuan, Hu Jiankun, Zhou Zongguang, Sun Xiaofeng
Abstract excerpt
The cAMP/PKA signalling events regulated by A-kinase anchoring proteins 10 (AKAP10) is involved in tumorigenesis. Previous study showed that AKAP10 polymorphism (2073 A/G, I646V) was associated with colorectal cancer risk. However, there was no literature reporting the role of AKAP10 in the pathogenesis of colorectal cancer. The aim of the study was to investigate the clinicopathologic significance of A-kinase...
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