Article
Alterations of microRNAs contribute to colon carcinogenesis.
Seminars in oncology - 1 Dec 2011
Schetter Aaron J, Harris Curtis C
Abstract excerpt
MicroRNAs are being evaluated as biomarkers and therapeutic targets for colon cancer. MicroRNAs have a functional role in the initiation and progression of colon cancer. Altered microRNA expression is found in tumors and their expression patterns may serve as useful cancer biomarkers. Polymorphisms in microRNAs or microRNA binding sites may modify the risk of developing cancer. As we continue to improve our...
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