Article
Structural variation occurring in the hemagglutinin of influenza virus A/turkey/Oregon/71 during adaptation to different cell types.
Virology - 1 Jun 1990
Orlich M, Khátchikian D, Teigler A, Rott R
Abstract excerpt
The influenza virus A/turkey/Oregon/71 (H7N3) has been adapted to grow in MDCK or chicken embryo cells (CEC) in the absence of trypsin. Changes occurred in the biological properties of the virus variants selected, depending on the cell type used for adaptation. They coincided with enhanced hemagg...
Topics
- Adaptation, Physiological
- Amino Acid Sequence
- Animals
- Base Sequence
- Cell Line
- DNA, Viral
- Electrophoresis, Polyacrylamide Gel
- Glycosylation
- Hemagglutinins, Viral
- Influenza A virus
- Molecular Sequence Data
- Mutation
- RNA, Viral
- Viral Plaque Assay