Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Structural variation occurring in the hemagglutinin of influenza virus A/turkey/Oregon/71 during adaptation to different cell types.

Virology - 1 Jun 1990

Orlich M, Khátchikian D, Teigler A, Rott R

Abstract excerpt

The influenza virus A/turkey/Oregon/71 (H7N3) has been adapted to grow in MDCK or chicken embryo cells (CEC) in the absence of trypsin. Changes occurred in the biological properties of the virus variants selected, depending on the cell type used for adaptation. They coincided with enhanced hemagglutinin (HA) activation by intracellular proteolytic cleavage. In the case of MDCK cell selected variants growth,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Base Sequence
Share to Cell Line

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA, Viral

Share to Electrophoresis, Polyacrylamide Gel

Share to Molecular Sequence Data

Share to Mutation

Share to RNA, Viral

Source

Identifiers

PMID: 2345964
DOI: 10.1016/0042-6822(90)90023-k

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Structural variation occurring in the hemagglutinin of influenza virus A/turkey/Oregon/71 during adaptation to different cell types.PMID 2345964Read ↗

Generation of seal influenza virus variants pathogenic for chickens, because of hemagglutinin cleavage site changes.Semantic proximity Read ↗

Protein mutations following adaptation of avian influenza viruses in different biological systems.Semantic proximity Read ↗

Non-basic amino acids in the hemagglutinin proteolytic cleavage site of a European H9N2 avian influenza virus modulate virulence in turkeys.Semantic proximity Read ↗

Molecular adaptation of an H7N3 wild duck influenza virus following experimental multiple passages in quail and turkey.Semantic proximity Read ↗

Substitution Arg140Gly in HA/H7 Reduced the Virulence Highly Pathogenic Avian Influenza Virus H7N1Semantic proximity Read ↗

Importance of conserved amino acids at the cleavage site of the haemagglutinin of a virulent avian influenza A virus.Semantic proximity Read ↗

Characteristics of influenza virus genome mutations.Semantic proximity Read ↗

Replication and adaptive mutations of low pathogenic avian influenza viruses in tracheal organ cultures of different avian species.Semantic proximity Read ↗

Substitution Arg140Gly in HA/H7 attenuated highly pathogenic avian influenza virus FPV/Rostock/34 (H7N1)Semantic proximity Read ↗

Compensatory Mutations in Avian Influenza H7N1 Hemagglutinin Drive Avian Host Adaptation and Antigenic Drift without Enhancing Replication in Human CellsSemantic proximity Read ↗

The role of influenza-A virus and coronavirus viral glycoprotein cleavage in host adaptationSemantic proximity Read ↗

Acquisition of a polybasic hemagglutinin cleavage site by a low-pathogenic avian influenza virus is not sufficient for immediate transformation into a highly pathogenic strain.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.