Article
The function of the vaccinia hemagglutinin in the proteolytic activation of infectivity.
Virology - 1 Jun 1990
Oie M, Shida H, Ichihashi Y
Abstract excerpt
The vaccinia virus hemagglutinin (HA) has specific affinity for the structural protein, VP37K. The nature of this affinity and its relationship to the function of the HA were analyzed using HA mutants. The VP37K reactive site of the HA molecule is located in its transmembrane region, and the vaccinia virus HA associates with the viral particle via the VP37K-HA affinity. The viruses possessing an HA with fusion...
Topics
- Adsorption
- Animals
- Blotting, Western
- Cell Fractionation
- Cell Line
- Cytoplasm
- Electrophoresis, Polyacrylamide Gel
- Hemagglutinins, Viral
- Mutation
- Vaccinia virus
- Vero Cells
- Viral Structural Proteins