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Article

Targeted and random mutagenesis of Ehrlichia chaffeensis for the identification of genes required for in vivo infection.

PLoS pathogens - 1 Feb 2013

Cheng Chuanmin, Nair Arathy D S, Indukuri Vijaya V, Gong Shanzhong, Felsheim Roderick F, Jaworski Deborah, Munderloh Ulrike G, Ganta Roman R

Abstract excerpt

Ehrlichia chaffeensis is a tick transmitted pathogen responsible for the disease human monocytic ehrlichiosis. Research to elucidate gene function in rickettsial pathogens is limited by the lack of genetic manipulation methods. Mutational analysis was performed, targeting to specific and random i...

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PMID: 23459099
DOI: 10.1371/journal.ppat.1003171
PMCID: PMC3573109

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23459099-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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