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Article

Impact of Three Different Mutations in Ehrlichia chaffeensis in Altering the Global Gene Expression Patterns.

Scientific reports - 18 Apr 2018

Kondethimmanahalli Chandramouli, Ganta Roman

Abstract excerpt

The rickettsial pathogen Ehrlichia chaffeensis causes a tick-borne disease, human monocytic ehrlichiosis. Mutations within certain genomic locations of the pathogen aid in understanding the pathogenesis and in developing attenuated vaccines. Our previous studies demonstrated that mutations in different genomic sites in E. chaffeensis caused variable impacts on their growth and attenuation in vertebrate and tick...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29670161
DOI: 10.1038/s41598-018-24471-3
PMCID: PMC5906474

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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