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Article

Genetic variants of FOXP3 influence graft survival in kidney transplant patients.

Human immunology - 1 Jun 2013

Engela Anja U, Boer Karin, Roodnat Joke I, Peeters Annemiek M A, Eilers Paul H, Kal-van Gestel Judith A, Rivadeneira Fernando, Weimar Willem, Baan Carla C

Abstract excerpt

FOXP3(+) regulatory T cells (Treg) play a role in controlling alloreactivity. It has been shown that short (GT)n dinucleotide repeats (≤(GT)15; S) in the promoter region of the FOXP3 gene enhance the promoter activity when compared to long (GT)n repeats (≥(GT)16; L). The present study retrospecti...

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Share to Dinucleotide Repeats
Share to Forkhead Transcription Factors
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Graft Rejection

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Share to Polymorphism, Genetic

Source

Identifiers

PMID: 23459079
DOI: 10.1016/j.humimm.2013.02.008

Genes

FOXP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23459079-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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