Article
Association of functional genetic variants of transcription factor Forkhead Box P3 and Nuclear Factor-κB with end-stage renal disease and renal allograft outcome.
Gene - 25 Apr 2016
Misra Maneesh Kumar, Mishra Aditi, Pandey Shashi Kant, Kapoor Rakesh, Sharma Raj Kumar, Agrawal Suraksha
Abstract excerpt
BACKGROUND: The transcription factor FOXP3 and NF-κB regulates the expression of various genes that play an important role in the regulation of renal inflammation. We investigated the association of FOXP3 (rs2232365, rs3761548, rs5902434 and rs2294021) and NF-κB1 (rs28362491 and ) gene variants in susceptibility and prognosis of end stage renal disease (ESRD) and renal allograft outcome. METHODS: We...