Article
NQO1 609C>T polymorphism interaction with tobacco smoking and alcohol drinking increases colorectal cancer risk in a Chinese population.
Gene - 25 May 2013
Peng Xian-E, Jiang Ying-Ying, Shi Xi-Shun, Hu Zhi-Jian
Abstract excerpt
BACKGROUND: NAD (P)H:quinone oxidoreductase (NQO1) catalyzes the activation of some environmental procarcinogens present in tobacco smoke or the diet. We conducted a hospital-based case-control study to evaluate the potential association between NQO1 609C>T polymorphisms and colorectal cancer risk in a Chinese population. METHODS: The study population comprised 672 histologically confirmed colorectal cancer...
Topics
- Adult
- Aged
- Alcohol Drinking
- Asian People
- Case-Control Studies
- Colorectal Neoplasms
- Diet
- Female
- Fruit
- Gene-Environment Interaction
- Genetic Predisposition to Disease