Article
High prevalence of mucosa-associated E. coli producing cyclomodulin and genotoxin in colon cancer.
PloS one - 1 Jan 2013
Buc Emmanuel, Dubois Damien, Sauvanet Pierre, Raisch Jennifer, Delmas Julien, Darfeuille-Michaud Arlette, Pezet Denis, Bonnet Richard
Abstract excerpt
Some Escherichia coli strains produce toxins designated cyclomodulins (CMs) which interfere with the eukaryotic cell cycle of host cells, suggesting a possible link between these bacteria and cancers. There are relatively few data available concerning the colonization of colon tumors by cyclomodulin- and genotoxic-producing E. coli. We did a qualitative and phylogenetic analysis of mucosa-associated E. coli...
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