Article
Role of bacterial surface structures on the interaction of Klebsiella pneumoniae with phagocytes.
PloS one - 1 Jan 2013
March Catalina, Cano Victoria, Moranta David, Llobet Enrique, Pérez-Gutiérrez Camino, Tomás Juan M, Suárez Teresa, Garmendia Junkal, Bengoechea José A
Abstract excerpt
Phagocytosis is a key process of the immune system. The human pathogen Klebsiella pneumoniae is a well known example of a pathogen highly resistant to phagocytosis. A wealth of evidence demonstrates that the capsule polysaccharide (CPS) plays a crucial role in resistance to phagocytosis. The amoeba Dictyostelium discoideum shares with mammalian macrophages the ability to phagocytose and kill bacteria. The fact...
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