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Article

Non-homologous end-joining pathway associated with occurrence of myocardial infarction: gene set analysis of genome-wide association study data.

PloS one - 1 Jan 2013

Verschuren Jeffrey J W, Trompet Stella, Deelen Joris, Stott David J, Sattar Naveed, Buckley Brendan M, Ford Ian, Heijmans Bastiaan T, Guchelaar Henk-Jan, Houwing-Duistermaat Jeanine J, Slagboom P Eline, Jukema J Wouter

Abstract excerpt

PURPOSE: DNA repair deficiencies have been postulated to play a role in the development and progression of cardiovascular disease (CVD). The hypothesis is that DNA damage accumulating with age may induce cell death, which promotes formation of unstable plaques. Defects in DNA repair mechanisms ma...

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Identifiers

PMID: 23457540
DOI: 10.1371/journal.pone.0056262
PMCID: PMC3574159

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23457540-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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