Article
Developing genetic epidemiological models to predict risk for nasopharyngeal carcinoma in high-risk population of China.
PloS one - 1 Jan 2013
Ruan Hong-Lian, Qin Hai-De, Shugart Yin Yao, Bei Jin-Xin, Luo Fu-Tian, Zeng Yi-Xin, Jia Wei-Hua
Abstract excerpt
To date, the only established model for assessing risk for nasopharyngeal carcinoma (NPC) relies on the sero-status of the Epstein-Barr virus (EBV). By contrast, the risk assessment models proposed here include environmental risk factors, family history of NPC, and information on genetic variants. The models were developed using epidemiological and genetic data from a large case-control study, which included...
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