Article
Genetic polymorphisms of CYP2E1 and DNA repair genes HOGG1 and XRCC1: association with hepatitis B related advanced liver disease and cancer.
Gene - 1 May 2013
Bose Sujoy, Tripathi Dinesh M, Sukriti, Sakhuja Puja, Kazim Syed N, Sarin Shiv K
Abstract excerpt
A population based case-control study was designed to explore the genetic risk factors for hepatitis B virus (HBV) related liver disease susceptibility. A total of 424 subjects comprising 210 controls, 50 acute HBV (AVH), 84 chronic HBV (CHBV), 25 HBV related cirrhosis and 55 HBV related hepatoce...
Topics
- Adult
- Aged
- Carcinoma, Hepatocellular
- Cytochrome P-450 CYP2E1
- DNA Damage
- DNA Glycosylases
- DNA Repair
- DNA-Binding Proteins
- Epistasis, Genetic
- Female
- Genetic Predisposition to Disease
- Genotype
- Hepatitis B
- Hepatitis B virus
- Humans
- Liver Neoplasms
- Male
- Middle Aged