Article
Polymorphism of DNA repair gene XRCC1 and hepatitis-related hepatocellular carcinoma risk in Indian population.
Molecular and cellular biochemistry - 1 Jul 2009
Kiran Manjula, Saxena Roli, Chawla Yogesh K, Kaur Jyotdeep
Abstract excerpt
BACKGROUND: Hepatocellular carcinoma (HCC) is one of the life-threatening malignancies worldwide with hepatitis B and C virus infection as the major risk factor. The risk of HCC might also increase because of the hereditary genetic defects in DNA repair genes. In this regard, X-ray cross-complementing group 1 gene (XRCC1) is a major DNA repair gene involved in base excision repair (BER). AIM: The present study...
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