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Article

Interleukin-1 has opposing effects on connective tissue growth factor and tenascin-C expression in human cardiac fibroblasts.

Matrix biology : journal of the International Society for Matrix Biology - 24 Apr 2013

Maqbool Azhar, Hemmings Karen E, O'Regan David J, Ball Stephen G, Porter Karen E, Turner Neil A

Abstract excerpt

Cardiac fibroblasts (CF) play a central role in the repair and remodeling of the heart following injury and are important regulators of inflammation and extracellular matrix (ECM) turnover. ECM-regulatory matricellular proteins are synthesized by several myocardial cell types including CF. We investigated the effects of pro-inflammatory cytokines on matricellular protein expression in cultured human CF. cDNA...

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Source

Identifiers

PMID: 23454256
DOI: 10.1016/j.matbio.2013.02.003

Genes

CCN2
TNC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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